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br Introduction The term autophagy was coined by Christian
2021-09-15

Introduction The term “autophagy” was coined by Christian de Duve in 1963 to describe the process of removing and degrading intracellular components such as unused proteins and damaged organelles through lysosomes [1,2]. Autophagy has been divided into three main types, namely, macroautophagy, mi
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Moreover studies on subcellular localization of FBPase
2021-09-15

Moreover, studies on subcellular localization of FBPase in carp heart and smooth muscle revealed nuclear localization of the enzyme. Previously, we have unequivocally demonstrated the presence of FBPase in the nuclei of mammalian cardiomyocytes (Gizak and Dzugaj, 2003) and myocytes (Gizak et al., 20
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The feasibility of using the Fas
2021-09-15

The feasibility of using the Fas/Fas ligand (FasL) system to target vascular progenitor AXL1717 synthesis contributing to intimal hyperplasia has been shown in many studies [[18], [19], [20], [21], [22], [23], [24]]. Fas receptor, a member of tissue necrosis factor family, is a death receptor that
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br Acknowledgements The authors have
2021-09-15

Acknowledgements The authors have no ethical conflicts to disclose. The authors have no conflicts of interest to declare. This work was funded by the Research Council of Lithuania. Introduction This paper studies whether there is a causal influence of the risk-taking incentives provided by op
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br Introduction Ovarian cancer patients have the highest mor
2021-09-15

Introduction Ovarian cancer patients have the highest mortality rate amongst patients with gynecologic cancers. The 10-year survival rate of ovarian cancer patients is cancer Chlortetracycline HCl with BRCA1/2 mutation [2]. Several studies have indicated the role of dysregulation of histone met
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The newest histamine receptor to be discovered
2021-09-15

The newest histamine receptor to be discovered is the H4 receptor, which was identified in humans and cloned in 2000 (Thurmond, 2010). Genetically, the H4 receptor is closely related to the H3 receptor, but is restricted to phosphodiesterase inhibitors within the spleen, intestines and thymus, and
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Certainly the immune relevance of Hippo becomes more complic
2021-09-15

Certainly, the immune relevance of Hippo becomes more complicated and divergent in the vertebrates than in Drosophila. In terms of inflammation of mammalians, the stories are diversified (Fig. 2). Previously, MST1/2 has been well characterized not only as a controller of lymphocytes adhesion and mi
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In this new therapeutic era nucleic acid
2021-09-15

In this new therapeutic era, nucleic VX-950 synthesis amplification tests (NAATs) remain critically useful. NAATs are recommended to detect HCV RNA in blood following initial serologic diagnosis of HCV infection, to distinguish between spontaneous resolution and progression to chronic infection [7].
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br The SRP SR Heterodimer GTPase Tangos Drive
2021-09-15

The SRP/SR Heterodimer: GTPase Tangos Drive Co-Translational Protein Targeting SRP and SR mediate a universally conserved protein targeting pathway responsible for the delivery of 25–30% of newly synthesized proteome to the eukaryotic endoplasmic reticulum (ER) or the bacterial plasma membrane 11
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br Acknowledgements We thank the support of the
2021-09-14

Acknowledgements We thank the support of the National Natural Science Foundation of China (NSFC) project 81501342 and support from the Disciplinary Group of Oncology and Immunology program of Xinxiang Medical University. Introduction First described as a new clinical entity in 1981, the Acqui
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Tetracaine HCl australia In breeding season small mammals in
2021-09-14

In breeding season, small mammals increase dispersal and social communication to maximize their opportunity to mate. In the present study, we found that gerbils in April showed more locomotion and exploratory behavior in the open field test. Moreover, subadult gerbils in April and July were more lik
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With taurine or other molecules that
2021-09-14

With taurine, or other molecules that might be transported by Eaat2, an important area of research will be how such a chemical regulates sleep. Indeed, taurine has been described to act on the nervous system in disparate ways — it can act as an inhibitory neurotransmitter, but also has a well-charac
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Both anxiety like behavior and sucrose preference intake wer
2021-09-14

Both anxiety-like behavior and sucrose preference/intake were reduced in GPR40/FFAR1 KO male mice, while social behavior was normal in KO mice. These findings indicate that brain GPR40/FFAR1 is involved in the modulation of anxiety- and depression-like behavior in rodents. Previous studies have demo
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We report here a patient with a one base frame
2021-09-14

We report here a patient with a one-base frame-shift deletion in the PURA gene that presented an unusual phenotype including persistent hypoglycorrhachia. We propose a possible link between hypoglycorrhachia and PURA dysfunction postulating PURA as a GLUT1 regulator. We therefore hypothesize that mu
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Analysis of genomic neighborhoods has helped resolve questio
2021-09-14

Analysis of genomic neighborhoods has helped resolve questions concerning the orthology of receptors for peptides similar to glucagon (Ng et al., 2010, Irwin and Prentice, 2011, Wang et al., 2012, Hwang et al., 2013). Using a diverse array of species with available genome sequence (see Fig. 4) the g
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