• Characterization factor is another variable suggested in the

  2020-04-30

  

  Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain

• The mechanism underlying the increased PON levels

  2020-04-30

  

  The mechanism underlying the increased PON1 levels found in greenhouse workers may be accounted for by an increased protein xylometazoline following pesticide interaction with different nuclear receptors as also occurs with other chemicals, such as polyphenols and statins [28]. A number of nuclear

• br The estrogen receptors History and

  2020-04-30

  

  The estrogen receptors: History and discovery In 1958, Elwood Jensen discovered the estrogen receptor, the first receptor ever encountered for any hormone, by showing that reproductive female tissues were able to uptake estrogen from the circulation by binding to proteins. He later demonstrated t

• PGE EP activation has been

  2020-04-30

  

  PGE2-EP4 activation has been found to attenuate the activation of microglia and to prevent lipid peroxidation and pro-inflammatory gene expression in a murine model of lipopolysaccharide (LPS)-induced mao inhibitors inflammation [15]. Moreover, PGE2/EP4 signaling has elicited a protective function

• MI-773 In the present study BACH downregulation did not corr

  2020-04-30

  

  In the present study, BACH1 downregulation did not correlate with nuclear accumulation of NRF2, suggesting that these changes were triggered via an independent mechanism. BACH1 is a transcriptional repressor that is regulated by heme. Heme binding to the BACH1 C-terminal domain inhibits BACH1 DNA bi

• In addition to playing important roles in the

  2020-04-30

  

  In addition to playing important roles in the immune system, EBI2 is also expressed in the bioactive of the central nervous system (CNS), namely astrocytes, and this receptor regulates astrocyte signalling, as well as astrocyte cell migration (Rutkowska et al., 2015, Rutkowska et al., 2016a). Moreo

• br Ubiquitination and deubiquitination pathways Ubiquitinati

  2020-04-30

  

  Ubiquitination and deubiquitination pathways Ubiquitination is a part of the post-translational modification (PTM) process. Ubiquitination affects proteins in various ways, but its main functions are to signal protein degradation via the 26S proteasome, modify cellular location of proteins, affec

• Interestingly all three lesions that significantly inhibited

  2020-04-30

  

  Interestingly, all three lesions that significantly inhibited transcription – CPD, εA and the AP site, – promoted insertion of β-Sitosterol mg residues opposite the damaged nucleotide. Thus, bacterial RNAP seems to follow the so-called ‘A-rule’ for incorporation of nucleotides opposite AP-sites and

• br Endothelial mechanotransduction br Apoptosis

  2020-04-30

  

  Endothelial mechanotransduction Apoptosis Death associated protein kinase Conclusion DAPK is localized to the AI-10-49 network, and promotes actomyosin contractility. DAPK stabilizes stress fibers by phosphorylation of MLC (Bialik et al., 2004, Kuo et al., 2003). In endothelial cells DA

• In summary the reduction of one or more

  2020-04-30

  

  In summary, the reduction of one or more pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, IL-8 was observed in almost all the monoterpenes studied. Increased levels of the anti-inflammatory cytokine IL-10 was shown to play a prominent function in the anti-inflammatory effect of monoterpenes,

• In humans individual differences in prefrontal dopamine are

  2020-04-29

  

  In humans, individual differences in prefrontal dopamine are partially caused by the Val158Met single-nucleotide polymorphism on the catechol-O-methyltransferase gene (COMT). This gene controls activity of the COMT enzyme, which degrades extracellular catecholamines including dopamine. The Val varia

• br Introduction Pattern separation is the ability

  2020-04-29

  

  Introduction Pattern separation is the ability to make distinct representations from highly overlapping information, a process which is important for memory encoding (Clelland et al., 2009). For correct pattern separation, old information needs to be retrieved and compared to new information. If

• Two key enzymes play important

  2020-04-29

  

  Two key enzymes play important roles in the bioconversion of xylitol from d-arabitol, namely d-arabitol dehydrogenase (ArDH) and NADH-dependent xylitol dehydrogenase (XDH), respectively (Qi et al., 2014). In an earlier study, we developed a high xylitol yield strain by expressing xdh in E. coli BL21

• Some studies have demonstrated that BMSCs

  2020-04-29

  

  Some studies have demonstrated that BMSCs can provide several trophic and growth factors that play important roles in cell survival, angiogenesis, and BMSC differentiation, but not cell replacement (Peled et al., 1999, Shen et al., 2007, Ji et al., 2004). This paracrine effect of BMSCs is a potentia

• br Materials and methods br Results br

  2020-04-29

  

  Materials and methods Results Discussion Cisplatin, as one member of a class of platinum-containing anti-cancer drugs, which displays a great deal of clinical activity on a wide variety of solid tumors. In addition, cisplatin often used in combination with other chemotherapy drugs to treat

16132 records 880/1076 page Previous Next First page 上5页 876877878879880 下5页 Last page