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br Materials and methods br Results br Discussion In the
2019-12-31
Materials and methods Results Discussion In the past decade, GWAS have attempted to identify genetic variants that confer risk for many human diseases, whose inherited components remain unexplained (Manolio et al., 2009). In a few cases risk variants identified by GWAS have paved the way fo
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br Acknowledgments We thank the Lapaha
2019-12-31
Acknowledgments We thank the Lapaha Community and Nobles (His Serene Highness Prince Kalaniuvalu Fotofili, Her Serene Highness Princess Marcella Taumoepeau Tupou Kalaniuvalu Fotofili and Her Royal Highness Mele Siu\'ilikutapu Kalaniuvalu Fotofili) and the Ministry of Internal Affairs (Government
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br Genomic actions in the breast br Conclusion
2019-12-31
Genomic actions in the breast Conclusion Clinical studies suggest that progesterone and/or progestins may play a decisive role in the development of breast cancer in women using hormone therapy or oral contraceptives [3], [4]. However, this data are controversial to most experimental investiga
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RHA is an agricultural by product obtained from
2019-12-31
RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the RN486 generation processes [8], [9]. If RHA produced at less than 700 °C, it chemically possess
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br Results with scrubbing process Based on the discussion of
2019-12-30
Results with scrubbing process Based on Clofarabine australia discussion of Section 4.4 and area availability results of the previous section, scrubbing process, at the pixel processing rate, was included to mitigate error accumulation on the arrays and on the line-buffer. Eight sequential signal
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br Pathophysiology of premature ovarian failure By the age o
2019-12-30
Pathophysiology of premature ovarian failure By the age of 40 years, 1% of women spontaneously develop POF [18]. The normal menopause occurs at an average age of 51 years [19] and results from ovarian follicle depletion [20], whereas POF is a heterogeneous disorder and can result from either foll
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The mitogen activated protein kinase MAPK pathway is a
2019-12-30
The mitogen-activated protein kinase (MAPK) pathway is a highly conserved module that mediates the transduction of signals from the cell surface to the nucleus (M. Köbel et al., 2005), meanwhile, it is known to be activated by a wide array of signals ranging from growth and differentiation factors t
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Baicalein trihydroxyflavone was first isolated from the
2019-12-30
Baicalein (5,6,7- trihydroxyflavone) was first isolated from the roots of Scutellaria baicalensis Georgi (Lamiaceae family), a medicinal plant with diverse therapeutic implications; antibacterial, antiviral, and anti-inflammatory properties. It has been found that baicalein benefits neuroinflammatio
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Several research groups have disclosed
2019-12-30
Several research groups have disclosed potent and selective DGAT-1 inhibitors from several chemically-distinct series. Pre-clinical studies with these compounds have confirmed that small molecule DGAT-1 inhibitors can elicit metabolic outcomes comparable to those observed in DGAT-1−/− mice.19, 20, 2
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Tibolone is also efficacious on bone in elderly
2019-12-29
Tibolone is also efficacious on bone in elderly women and induces a clear reduction in bone turnover markers [50], [51]. Rymer et al. showed that, after 10 years of treatment with tibolone, the difference in bone mineral density compared with a placebo group was more than 12% for both lumbar spine
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Industrial fermentation aims to produce valuable products fr
2019-12-29
Industrial fermentation aims to produce valuable products from cheap feedstocks by utilizing diverse microbial functions through aerobic or anaerobic fermentation [[8], [9], [10]]. During anaerobic fermentation, the reducing power is mostly directed to product synthesis rather than being oxidized, r
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Bmp products such as Fig
2019-12-29
Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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T cell infiltration is an important
2019-12-29
T cell infiltration is an important predictive biomarker for the PD-1 blockade, and it is closely associated with a good prognosis. In our study, we found that T cells were low and exhausted within the tumor microenvironment and were distributed in the tumor margin. Anti-PD-1 treatment reduced PD-1
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Pahlavanzadeh and Fakouri Baygi employed
2019-12-29
Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the farnesoid x receptor of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achi
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This study has several limitations First
2019-12-29
This study has several limitations. First, despite the relatively large number of participants for a pharmacological neuroimaging study, sample sizes for examining the modulation of THC effects by COMT ace inhibitor were small. Therefore, these particular findings should be interpreted with caution
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