• telomerase inhibitor DDX belongs to the DEAD box family of p

  2019-07-02

  

  DDX3 belongs to the DEAD-box family of proteins, ATP-dependent RNA helicases characterized by the presence of a highly conserved helicase core domain [13]. This catalytic core is composed of two RecA-like domains containing motifs involved in ATP binding/hydrolysis, RNA binding and helicase activity

• Calcium Colorimetric Assay Kit molecular br Experimental Pro

  2019-07-02

  

  Experimental Procedures Author Contributions H.G. and X.-Y.F. conceived and designed the project. H.G., D.V.D., and X.L. performed most of the experiments and analyzed the data. L.X. helped on Mettl8 KO ESC, RIP, and translational study. Y.S. performed FACS analysis. Y.W. helped with cardiomyo

• Exposure to UV instead of DMBA also produced

  2019-07-02

  

  Exposure to UV instead of DMBA also produced a sloughing and angiogenic response in transgenic, but not WT, mice, indicating that the epidermis of the BK5.EP4 mice has a much lower apoptosis threshold than WT mice, as suggested by others (Chun and Langenbach, 2007). Overall, these studies suggest th

• br Introduction Prostaglandin E PGE signals through separate

  2019-07-02

  

  Introduction Prostaglandin E2 (PGE2) signals through 4 separate G-protein coupled receptor sub-types (EP1, EP2, EP3 and EP4) to elicit a variety of physiological and pathophysiologic effects. EP2 and EP4 increase cAMP levels in the cell via adenylate cyclase activation, whereas EP3 inhibits cAMP

• br Chondroitin sulfate proteoglycans CSPGs are major compone

  2019-07-02

  

  Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix in cartilage. Each CSPG comprises a single core protein and attached chondroitin sulfate (CS), belonging to the glycosaminoglycan family of sugar chains. CSPGs and CS are involved in numerous biological and

• br Acknowledgments This work was supported by a grant from

  2019-07-02

  

  Acknowledgments This work was supported by a grant from the National Center for GM Crops (PJ008152) of the Next Generation BioGreen 21 Program funded by the Rural Development Administration, Republic of Korea, to W.T.K. Introduction Ubiquitin (Ub) has been considered as one of the most import

• br Mega cohort studies Remote monitoring collects a

  2019-07-01

  

  Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise

• Catheter ablation of a concealed

  2019-07-01

  

  Catheter ablation of a concealed right anteroseptal AV bypass tract was successfully performed in our patient. Catheter ablation of the anteroseptal accessory pathway did not affect normal AV conduction. The effective refractory period of the fast AV node was 380ms at a pacing leukotriene receptor a

• br Introduction Atrial fibrillation AF is

  2019-07-01

  

  Introduction Atrial fibrillation (AF) is the most clinically prevalent tachyarrhythmia [1,2]. AF is a potential risk factor for stroke, and AF-associated strokes are often severe, resulting in disability or death [3–6]. Anticoagulant therapy with the vitamin K antagonist warfarin reduces the risk

• Despite potassium administration her serum potassium concent

  2019-07-01

  

  Despite potassium administration, her serum potassium concentration did not normalize until 56h after admission because she W 54011 had taken hydrocortisone for pituitary adrenal insufficiency after surgery for a pituitary tumor. Under the persistent hypokalemic condition (K+=2.5–2.64mEq/L), alterna

• In the present study the timing of

  2019-07-01

  

  In the present study, the timing of the LA potentials in respect to the timing of the CSM potentials depended closely on the direction of impulse propagation across the interatrial connection at the proximal CS. Thus, a LA → CSM activation sequence was observed only when the wavefront traveled throu

• Parthenolide The increasing burden of NCDs

  2019-07-01

  

  The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as

• RVX-208 molecular Some health related topics are

  2019-07-01

  

  Some health-related topics are guaranteed to stir up heated debate in the general public whenever they RVX-208 molecular crop up in the news. Publishing a research paper on chronic fatigue syndrome, homoeopathy, or mode of childbirth is a recipe for a media field day, a lively letters section, and

• dna methyltransferase We modelled how the loss

  2019-07-01

  

  We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction

• Initial bone marrow biopsy was inadequate in size

  2019-07-01

  

  Initial bone marrow biopsy was inadequate in size for detailed examination and had severe crush artifact. The preserved focus of marrow showed hypercellularity with large, multinucleated, dysplastic megakaryocytes and megaloblastoid changes in erythroid series (Fig. 1B and C). There was no increase

15368 records 992/1025 page Previous Next First page 上5页 991992993994995 下5页 Last page